EDTA has been used for over 55 years in the health industry and is very safe and effective. The safest form of usage comes from topical application. Since we are constantly bombarded living in a toxic world, one must be proactive on a regular basis to remain in the best of health. EDTA is not a one-time treatment or cure. EZDtox Cream should be used for several months to obtain the desired results and then several times a week for maintenance thereafter. HOW TO APPLY – You will want to apply the cream to a thin-skinned area of your body which has minimal fat. Best areas are inner wrists, tops or sides of feet, back of the knee or forearms. DOSAGE & USE – It is recommended and safe to use 1 tsp. (4 pumps) of EZDtox Cream once nightly (or any time of day) for a good initial detoxification. Depending upon your level of exposure or toxicity, you may need to use a higher dosage for up to 180 days or more. Using less than the recommended daily dosage of 1 tsp. will still be effective, but will prolong results. It can also be used multiple times a day.